Top 10 Stem Cell Therapy Specialists in the US

Prolotherapy is a regenerative injection treatment used for some musculoskeletal pain, joint problems, ligament injuries, and tendon conditions.

Because treatment needs vary, choosing a qualified and experienced specialist is important. Prolotherapy may not be suitable for every condition.

Below are 10 US specialists selected for their documented experience, credentials, clinical work, teaching, or research in prolotherapy.

How We Selected These Prolotherapy Specialists

We selected these specialists based on their documented experience, medical credentials, and work in prolotherapy and regenerative medicine.

We also considered their clinical practice, research, and professional education.

Key factors included:

• Prolotherapy experience and training
• Relevant medical credentials
• Regenerative or musculoskeletal expertise
• Research, teaching, or professional recognition
• Current clinical practice

List of 10 Verified Prolotherapy Specialists in the US

Here are 10 US specialists with documented experience in prolotherapy and regenerative medicine.

Details about their expertise and professional backgrounds are provided below.

1. Dr. Blanki Cherubini, MD – Rhode Island
2. Dr. Donna Alderman, DO – California
3. Dr. Ross Hauser, MD – Florida
4. Dr. Sean Mulvaney, MD – Maryland
5. Dr. Dean Reeves, MD – Kansas
6. Dr. David Wang, DO – Washington, DC
7. Dr. Mayo Friedlis, MD – Virginia/Maryland
8. Dr. Steven Karageanes, DO – Michigan
9. Dr. Mark Cantieri, DO – Indiana
10. Dr. Suzanne Alt, DO – Missouri

The following sections explain each specialist’s experience, expertise, and prolotherapy-related work.

1. Dr. Blanki Cherubini, MD – Rhode Island

Dr. Blanki Cherubini, MD, is recognized among the top prolotherapy specialists in the US, with professional expertise in physical medicine, rehabilitation, and regenerative medicine.

She practices at The Pain Center of Rhode Island, where her clinical work emphasizes non-surgical approaches to musculoskeletal pain and injuries.

Key areas of expertise include:

• Prolotherapy and regenerative medicine
• Physical medicine and rehabilitation
• Chronic musculoskeletal pain
• Joint and sports-related injuries

Her experience in regenerative and musculoskeletal care makes her a notable specialist for patients considering prolotherapy in Rhode Island.

A consultation can help determine whether this treatment is appropriate for a patient’s specific condition and goals.

2. Dr. Donna Alderman, DO – California

Dr. Donna Alderman, DO, is a respected physician in orthopedic regenerative medicine and serves as Medical Director of the Hemwall Center for Orthopedic Regenerative Medicine in California.

She has practiced prolotherapy since the 1990s and has extensive experience in regenerative treatment.

Her work includes:

• Dextrose prolotherapy
• PRP prolotherapy
• Biocellular treatments
• Regenerative medicine education and research

Dr. Alderman’s clinical work is closely associated with the Hemwall tradition of prolotherapy, and her professional profile identifies her as prolotherapy board-certified.

Her medical education includes Cornell University and Western University of Health Sciences, along with experience in physician education and regenerative medicine research.

3. Dr. Ross Hauser, MD – Florida

Dr. Ross Hauser, MD, is a longstanding practitioner of prolotherapy and regenerative medicine based at Caring Medical in Fort Myers, Florida.

He is recognized for his extensive clinical experience with prolotherapy in the United States, having trained with prolotherapy physician Gustav Hemwall and practiced the treatment since the early 1990s.

His clinical and professional focus includes:

• Hackett-Hemwall-Hauser (H3) Prolotherapy
• Chronic musculoskeletal pain
• Joint instability and sports injuries
• Spine-related conditions
• Prolotherapy research and clinical education

Dr. Hauser has also published research on prolotherapy, including work examining lumbar instability and chronic low-back pain, adding a strong research component to his clinical experience.

4. Dr. Sean Mulvaney, MD – Maryland

Dr. Sean Mulvaney, MD, is a physician specializing in regenerative orthopedics and sports medicine in Annapolis, Maryland.

His practice provides non-surgical care for musculoskeletal, nerve, spine, and sports-related injuries across America.

His clinical expertise includes:

• Prolotherapy and PRP
• Ultrasound-guided procedures
• Osteoarthritis and tendinopathies
• Spine conditions and nerve entrapments
• Sports and musculoskeletal injuries

Dr. Mulvaney also has documented experience in medical teaching and research, supporting his broader work in regenerative and image-guided treatments.

5. Dr. Dean Reeves, MD – Kansas

Dr. Dean Reeves, MD, is a physician with a strong background in Physical Medicine and Rehabilitation, focusing on musculoskeletal pain and prolotherapy.

His clinical and research work has contributed to the field of regenerative medicine in the United States.

His expertise includes:

• Dextrose and platelet prolotherapy
• Chronic musculoskeletal pain
• Sprains, strains, and joint problems
• Prolotherapy research and clinical practice

Dr. Reeves co-authored a major review of dextrose prolotherapy covering basic science, clinical research, and treatment considerations.

His long-standing involvement in prolotherapy combines clinical experience with academic research.

6. Dr. David Wang, DO – Washington, DC

Dr. David Wang, DO, is a Physical Medicine and Rehabilitation physician known for his work in musculoskeletal ultrasound and regenerative medicine.

His clinical and teaching experience has helped advance image-guided regenerative care in America.

His professional focus includes:

• Prolotherapy and regenerative orthobiologics
• PRP treatments
• Diagnostic and interventional musculoskeletal ultrasound
• Physical Medicine and Rehabilitation

Dr. Wang completed his residency at Harvard Medical School/Spaulding Rehabilitation Hospital and has taught prolotherapy and regenerative medicine nationally and internationally since 2008.

His combination of clinical practice and education makes him a notable specialist in this field.

7. Dr. Mayo Friedlis, MD – Virginia/Maryland

Dr. Mayo Friedlis, MD, specializes in interventional pain medicine and Physical Medicine and Rehabilitation, with experience in image-guided injections and regenerative treatments.

His clinical work covers a range of musculoskeletal and spine-related conditions in the United States.

His areas of expertise include:

• Prolotherapy and regenerative treatments
• Interventional pain medicine
• Image-guided injections
• Musculoskeletal and spine conditions

Dr. Friedlis is board-certified in Physical Medicine and Rehabilitation, and his current physician profile specifically lists prolotherapy among his treatment options.

He has also been featured by the American Academy of Orthopedic Medicine in educational material covering prolotherapy, PRP, and stem-cell treatments.

8. Dr. Steven Karageanes, DO – Michigan

Dr. Steven Karageanes, DO, is a sports medicine physician in Michigan with particular experience in orthopedic, sports, and performing-arts injuries.

His practice provides non-surgical regenerative treatment options for patients in America.

His clinical focus includes:

• Prolotherapy and PRP
• Sports medicine
• Diagnostic musculoskeletal ultrasound
• Performing-arts and sports-related injuries

Dr. Karageanes has worked with dancers, performing artists, athletic programs, and professional productions.

His combination of sports medicine experience and regenerative treatment expertise makes him a notable physician in this field.

9. Dr. Mark Cantieri, DO – Indiana

Dr. Mark Cantieri, DO, has extensive experience in osteopathic medicine, musculoskeletal pain care, and prolotherapy.

He has practiced in the South Bend and Mishawaka area and has focused much of his career on musculoskeletal conditions.

His professional experience includes:

• Prolotherapy since 1997
• Musculoskeletal pain treatment
• Prolotherapy education and physician training
• Regenerative medicine

Dr. Cantieri has taught prolotherapy to physicians in the US and internationally and co-authored Principles of Prolotherapy, a medical textbook on the technique.

His long-term clinical and educational involvement is a key part of his professional profile.

10. Dr. Suzanne Alt, DO – Missouri

Dr. Suzanne Alt, DO, is an osteopathic physician whose professional areas include prolotherapy, Physical Medicine and Rehabilitation, and musculoskeletal care.

Her background combines osteopathic medicine with regenerative treatment approaches.

Her areas of focus include:

• Prolotherapy
• Physical Medicine and Rehabilitation
• Pain management
• Musculoskeletal care

The American Osteopathic Association of Prolotherapy Regenerative Medicine lists Dr. Alt as prolotherapy board-certified.

A physician directory also identifies prolotherapy among her specialties, supporting her experience in regenerative and musculoskeletal care in the United States.

Comparison of the Top Prolotherapy Specialists

Choosing a prolotherapy specialist often depends on their location, clinical focus, and experience.

The table below gives you a simple overview of these specialists and their main areas of expertise.

What Conditions Can Prolotherapy Specialists Treat?

Prolotherapy is mainly used in some practices for musculoskeletal conditions involving joints, ligaments, tendons, and other connective tissues.

Depending on the physician’s training, it may be considered for:

• Chronic joint pain
• Ligament injuries
• Tendon injuries and tendinopathy
• Osteoarthritis-related pain
• Low-back pain
• Neck pain
• Sports injuries
• Joint instability
• Certain overuse injuries

However, the evidence varies by condition.

Cleveland Clinic notes that prolotherapy is not a standard treatment for any particular disease or condition, while published research continues to investigate its potential role in musculoskeletal pain.

How Much Does Prolotherapy Cost in the US?

Prolotherapy costs vary across the United States based on the provider, treatment area, number of injections, and sessions required.

As a general guide, one prolotherapy session may cost around $200–$500.

Costs may also include:

• Initial consultation: Often charged separately
• Ultrasound guidance: May add to the treatment fee
• Multiple sessions: Increase the overall cost
• Insurance: Coverage can be limited or unavailable

Before treatment, ask the clinic for a complete cost estimate and confirm whether any part of the treatment is covered by your insurance.

How to Choose the Right Prolotherapy Specialist

Finding the right physician is about more than choosing a name from a list. Consider whether the doctor regularly treats your specific condition and has appropriate medical training.

Look for a specialist who:

1. Has documented experience with prolotherapy.
2. Understands your specific injury or pain condition.
3. Can explain the expected benefits and limitations.
4. Discusses conventional and alternative treatment options.
5. Uses imaging guidance when appropriate.
6. Clearly explains the number and cost of planned treatments.
7. Reviews potential risks and alternatives.
8. Does not promise guaranteed results.

It is also worth asking whether prolotherapy is appropriate for your particular diagnosis.

Since the evidence is still developing, an informed discussion with a qualified physician can help you understand where it fits among other treatment options.

Final Thoughts

The United States has physicians with diverse experience in prolotherapy and regenerative medicine, including physical medicine, rehabilitation, sports medicine, and pain management.

The specialists featured in this guide have documented clinical, educational, or research experience related to prolotherapy and musculoskeletal care.

Before choosing a specialist, consider their credentials, experience with your condition, treatment approach, costs, and the available evidence. A consultation can help determine whether prolotherapy is appropriate for you.

Platelet-rich plasma (PRP) therapy uses a concentrated portion of your own blood to support healing in injured or painful areas. It is commonly used in sports medicine, orthopaedics, and regenerative medicine.

Choosing a PRP specialist means looking beyond whether they offer PRP injections. Experience with musculoskeletal conditions, ultrasound-guided procedures, and regenerative treatments can also be important.

Below are 10 physicians with documented PRP-related expertise and experience in sports medicine, physical medicine, orthopaedics, or regenerative medicine.

What We Consider When Choosing PRP Therapy Specialists

We focused on publicly documented professional credentials and clinical expertise rather than patient ratings or an overall ranking of doctors.

Key factors included:

• Documented PRP or platelet-rich plasma experience
• Sports medicine, orthopaedics, or physical medicine and rehabilitation training
• Experience with musculoskeletal and sports-related conditions
• Regenerative medicine or orthobiologic expertise
• Musculoskeletal ultrasound and ultrasound-guided procedures
• Current affiliation with established medical institutions

Because PRP may not be appropriate for every condition, patients should discuss their diagnosis, treatment alternatives, expected outcomes, and potential risks with a qualified clinician.

10 Verified PRP Therapy Specialists in the US

Here are 10 physicians with documented experience in PRP therapy and related musculoskeletal care:

1. Dr. Blanki Cherubini, M.D.
2. Amanda M. Honsvall Hoefler, MD
3. Eric Berkson, MD
4. Kelly McInnis, DO
5. Michael Dakkak, DO
6. Evan Peck, MD
7. Shane A. Shapiro, MD
8. Ellie J. Jelsing, MD
9. Steve K. Poon, MD
10. Jane Konidis, MD

Detailed information about each specialist, including their PRP expertise and areas of care, is explained in the sections below.

1. Dr. Blanki Cherubini, M.D. — Rhode Island

Dr. Blanki Cherubini, M.D., is a leading PRP therapy specialist in the US who practices at the Pain Center of Rhode Island.

She has expertise in Physical Medicine and Rehabilitation, sports medicine, musculoskeletal care, regenerative medicine, diagnostic ultrasound, and ultrasound-guided injections.

Key Areas of Expertise

• PRP and regenerative medicine
• Sports and musculoskeletal medicine
• Diagnostic musculoskeletal ultrasound
• Ultrasound-guided injections
• Joint and tendon conditions

Her expertise in regenerative and orthobiologic treatments, combined with image-guided procedures, supports precise evaluation and targeted musculoskeletal care.

2. Amanda M. Honsvall Hoefler, MD — UCLA Health, Los Angeles, California

Dr. Amanda M. Honsvall Hoefler is a leading PRP therapy specialist at UCLA Health. She specializes in Primary Care Sports Medicine, musculoskeletal conditions, and non-surgical orthopaedic care.

Her expertise includes PRP and other orthobiologic injections.

Key Areas of Expertise

• PRP and orthobiologic injections
• Musculoskeletal ultrasound
• Ultrasound-guided joint injections
• Sports injuries and injury prevention

Her combination of sports medicine expertise, musculoskeletal ultrasound, and image-guided procedures supports precise and targeted care for patients considering PRP therapy.

3. Eric Berkson, MD — Mass General, Boston, Massachusetts

Dr. Eric Berkson is a highly regarded Sports Medicine Orthopaedic Surgeon at Mass General and an Assistant Professor of Orthopaedic Surgery at Harvard Medical School.

His clinical interests include platelet-rich plasma (PRP) and advanced treatment of sports-related musculoskeletal conditions.

Key Areas of Expertise

• PRP treatment
• Knee and shoulder injuries
• Cartilage and joint preservation
• Meniscus and ACL injuries
• Sports medicine and orthopaedic care

His experience in cartilage restoration, joint preservation, and complex sports injuries provides a strong foundation for comprehensive musculoskeletal care.

4. Kelly McInnis, DO — Mass General, Boston, Massachusetts

Dr. Kelly McInnis is a sports medicine physician and physiatrist at Mass General with specialized expertise in non-operative musculoskeletal care.

Her clinical interests include PRP, orthobiologic injections, sports injuries, and Physical Medicine and Rehabilitation.

Key Areas of Expertise

• PRP and orthobiologic injections
• Non-operative sports medicine
• Musculoskeletal ultrasound
• Diagnostic and interventional procedures
• Sports and overuse injuries

Her training in musculoskeletal ultrasound and regenerative injection techniques supports precise, non-surgical treatment for patients with sports and musculoskeletal conditions.

5. Michael Dakkak, DO — Cleveland Clinic, Florida

Dr. Michael Dakkak is a Cleveland Clinic sports medicine physician specializing in Primary Care Sports Medicine and non-operative orthopaedics.

His expertise includes PRP and other advanced orthobiologic treatments.

Key Areas of Expertise

• PRP injections
• Orthobiologic treatments
• Musculoskeletal ultrasound
• Ultrasound-guided procedures
• Non-operative orthopaedic care

His experience with regenerative medicine and image-guided procedures supports targeted treatment for a range of musculoskeletal conditions.

6. Evan Peck, MD — Cleveland Clinic, Florida

Dr. Evan Peck is a Cleveland Clinic sports medicine physician who provides care for both adult and adolescent patients.

His clinical services include PRP injections, regenerative medicine, and non-operative orthopaedic treatment.

Key Areas of Expertise

• PRP injections
• Regenerative medicine
• Musculoskeletal ultrasound
• Joint preservation
• Chronic tendinopathy

His expertise in ultrasound-guided procedures and joint preservation provides a comprehensive approach to sports and musculoskeletal conditions.

7. Shane A. Shapiro, MD — Mayo Clinic, Jacksonville, Florida

Dr. Shane A. Shapiro is a Mayo Clinic sports medicine physician and medical director of the Regenerative Medicine Therapeutics Program at Mayo Clinic’s Center for Regenerative Medicine.

His work focuses on regenerative treatments for musculoskeletal conditions.

Key Areas of Expertise

• PRP injections
• Regenerative medicine
• Orthobiologic treatments
• Chronic tendinopathies
• Osteoarthritis and joint pain

His clinical and research experience in PRP and regenerative medicine makes him an established physician in the field of musculoskeletal care.

8. Ellie J. Jelsing, MD — Mayo Clinic, Rochester, Minnesota

Dr. Ellie J. Jelsing is a Mayo Clinic sports medicine specialist in Rochester, Minnesota.

Her clinical focus includes PRP injections, ultrasound-guided treatments, and non-surgical care for musculoskeletal conditions.

Key Areas of Expertise

• PRP injections
• Ultrasound-guided procedures
• Joint and soft-tissue injections
• Osteoarthritis and tendinopathy
• Sports injuries

Her experience with image-guided treatments and sports medicine supports targeted care for joint, tendon, and soft-tissue conditions.

9. Steve K. Poon, MD — Mayo Clinic

Dr. Steve K. Poon is a Mayo Clinic sports medicine specialist focused on musculoskeletal conditions and sports-related problems.

His areas of focus include PRP injections and ultrasound-guided musculoskeletal procedures.

Key Areas of Expertise

• PRP injections
• Musculoskeletal ultrasound
• Ultrasound-guided injections
• Joint injections
• Soft-tissue procedures

His expertise in minimally invasive injection techniques supports comprehensive non-surgical care for musculoskeletal conditions.

10. Jane Konidis, MD — Mayo Clinic, Rochester, Minnesota

Dr. Jane Konidis is a Mayo Clinic physiatrist in Rochester, Minnesota, with expertise in Physical Medicine and Rehabilitation and regenerative treatments.

Her procedures include PRP and bone marrow aspirate concentrate injections.

Key Areas of Expertise

• PRP and orthobiologic treatments
• Bone marrow aspirate concentrate
• Musculoskeletal ultrasound
• Joint and soft-tissue injections
• Tendon and sports injuries

Her combination of regenerative medicine, ultrasound-guided treatment, and rehabilitation expertise supports comprehensive care for joint, tendon, and soft-tissue conditions.

Comparison of the Top PRP Therapy Specialists

The following table provides a quick overview of the specialists and the documented areas most relevant to PRP therapy.

What Makes These PRP Therapy Specialists Stand Out?

These physicians bring PRP into a broader approach to musculoskeletal care.

Their expertise often combines regenerative medicine, sports medicine, orthopaedics, rehabilitation, and diagnostic procedures.

Key Factors That Set Them Apart

• Specialized medical training in sports medicine, orthopaedics, or rehabilitation
• PRP and orthobiologic experience for various musculoskeletal conditions
• Ultrasound-guided procedures for more precise assessment and treatment
• Comprehensive evaluation before recommending PRP therapy
• Non-surgical treatment options alongside regenerative therapies

This broader expertise allows patients to understand whether PRP is suitable for their condition and how it may fit into their overall treatment plan.

Conditions PRP Specialists Commonly Treat

Depending on the physician and the individual diagnosis, PRP may be considered for conditions such as:

• Osteoarthritis and joint pain
• Tendinopathy and chronic tendon pain
• Sports injuries
• Muscle and soft-tissue injuries
• Knee and shoulder problems
• Tennis or golfer’s elbow
• Achilles and patellar tendon conditions
• Certain cartilage or joint-related problems

PRP is not appropriate for every injury or patient, so treatment should be based on an individual medical assessment.

How to Choose the Right PRP Specialist in the US

Choosing a PRP specialist starts with finding a physician whose expertise matches your condition.

A sports medicine physician may be suitable for an athletic injury, while a physiatrist may be a good option for non-surgical musculoskeletal care.

7 Things to Check Before Choosing a PRP Specialist

1. Relevant medical specialty – Look for experience with your specific condition or injury.
2. PRP experience – Ask how regularly the physician performs PRP injections.
3. Ultrasound guidance – Find out whether ultrasound is used when appropriate for accurate treatment.
4. Diagnosis and treatment plan – Understand what condition is being treated and why PRP is recommended.
5. Alternative treatments – Ask about other non-surgical or regenerative treatment options.
6. Number of treatments – Discuss how many PRP sessions may be needed and the expected recovery period.
7. Cost and follow-up care – Ask about the total treatment cost, follow-up appointments, and ongoing care.

These questions can help you understand whether the specialist’s experience, treatment approach, and services are appropriate for your individual needs.

PRP Therapy Cost in the US

The cost of PRP therapy in the US varies based on the treatment area, provider, location, and number of sessions needed. Insurance coverage may also vary.

Main Factors That Affect Cost

• Treatment area – Different conditions may have different costs.
• Number of sessions – More sessions can increase the total cost.
• Provider and location – Prices vary between specialists and cities.
• Additional care – Consultation, imaging, and follow-up visits may add to the cost.

Ask your specialist for the full cost before starting treatment.

Benefits of Having a Qualified PRP Specialist

A qualified PRP specialist can help determine whether PRP is right for your condition.

They can also identify the treatment area, explain what to expect, and discuss other options when needed.

5 Key Benefits of a Qualified PRP Specialist

• Accurate evaluation – Helps identify the cause of your pain or injury.
• Proper treatment planning – Determines whether PRP is suitable for your condition.
• Precise procedures – Ultrasound guidance can help target the treatment area when appropriate.
• Realistic expectations – Explains possible results, recovery, and follow-up care.
• Personalized care – Creates a treatment plan based on your condition, not a one-size-fits-all approach.

Final Thoughts

PRP therapy is used in sports medicine, orthopaedics, physical medicine, rehabilitation, and regenerative medicine. The specialists discussed above have experience with PRP or related musculoskeletal treatments.

The right specialist depends on your condition, location, medical specialty, and treatment needs. It is important to choose a physician whose expertise matches your specific problem.

Before starting PRP, have a detailed consultation to understand whether it is suitable for you, along with the possible benefits, risks, alternatives, recovery, and cost.