Prolotherapy is a regenerative injection treatment used for some musculoskeletal pain, joint problems, ligament injuries, and tendon conditions.
Because treatment needs vary, choosing a qualified and experienced specialist is important. Prolotherapy may not be suitable for every condition.
Below are 10 US specialists selected for their documented experience, credentials, clinical work, teaching, or research in prolotherapy.
How We Selected These Prolotherapy Specialists
We selected these specialists based on their documented experience, medical credentials, and work in prolotherapy and regenerative medicine.
We also considered their clinical practice, research, and professional education.
Key factors included:
- Prolotherapy experience and training
- Relevant medical credentials
- Regenerative or musculoskeletal expertise
- Research, teaching, or professional recognition
- Current clinical practice
List of 10 Verified Prolotherapy Specialists in the US
Here are 10 US specialists with documented experience in prolotherapy and regenerative medicine.
Details about their expertise and professional backgrounds are provided below.
- Dr. Blanki Cherubini, MD – Rhode Island
- Dr. Donna Alderman, DO – California
- Dr. Ross Hauser, MD – Florida
- Dr. Sean Mulvaney, MD – Maryland
- Dr. Dean Reeves, MD – Kansas
- Dr. David Wang, DO – Washington, DC
- Dr. Mayo Friedlis, MD – Virginia/Maryland
- Dr. Steven Karageanes, DO – Michigan
- Dr. Mark Cantieri, DO – Indiana
- Dr. Suzanne Alt, DO – Missouri
The following sections explain each specialist’s experience, expertise, and prolotherapy-related work.
1. Dr. Blanki Cherubini, MD – Rhode Island
Dr. Blanki Cherubini, MD, is recognized among the top prolotherapy specialists in the US, with professional expertise in physical medicine, rehabilitation, and regenerative medicine.
She practices at The Pain Center of Rhode Island, where her clinical work emphasizes non-surgical approaches to musculoskeletal pain and injuries.
Key areas of expertise include:
- Prolotherapy and regenerative medicine
- Physical medicine and rehabilitation
- Chronic musculoskeletal pain
- Joint and sports-related injuries
Her experience in regenerative and musculoskeletal care makes her a notable specialist for patients considering prolotherapy in Rhode Island.
A consultation can help determine whether this treatment is appropriate for a patient’s specific condition and goals.
2. Dr. Donna Alderman, DO – California
Dr. Donna Alderman, DO, is a respected physician in orthopedic regenerative medicine and serves as Medical Director of the Hemwall Center for Orthopedic Regenerative Medicine in California.
She has practiced prolotherapy since the 1990s and has extensive experience in regenerative treatment.
Her work includes:
- Dextrose prolotherapy
- PRP prolotherapy
- Biocellular treatments
- Regenerative medicine education and research
Dr. Alderman’s clinical work is closely associated with the Hemwall tradition of prolotherapy, and her professional profile identifies her as prolotherapy board-certified.
Her medical education includes Cornell University and Western University of Health Sciences, along with experience in physician education and regenerative medicine research.
3. Dr. Ross Hauser, MD – Florida
Dr. Ross Hauser, MD, is a longstanding practitioner of prolotherapy and regenerative medicine based at Caring Medical in Fort Myers, Florida.
He is recognized for his extensive clinical experience with prolotherapy in the United States, having trained with prolotherapy physician Gustav Hemwall and practiced the treatment since the early 1990s.
His clinical and professional focus includes:
- Hackett-Hemwall-Hauser (H3) Prolotherapy
- Chronic musculoskeletal pain
- Joint instability and sports injuries
- Spine-related conditions
- Prolotherapy research and clinical education
Dr. Hauser has also published research on prolotherapy, including work examining lumbar instability and chronic low-back pain, adding a strong research component to his clinical experience.
4. Dr. Sean Mulvaney, MD – Maryland
Dr. Sean Mulvaney, MD, is a physician specializing in regenerative orthopedics and sports medicine in Annapolis, Maryland.
His practice provides non-surgical care for musculoskeletal, nerve, spine, and sports-related injuries across America.
His clinical expertise includes:
- Prolotherapy and PRP
- Ultrasound-guided procedures
- Osteoarthritis and tendinopathies
- Spine conditions and nerve entrapments
- Sports and musculoskeletal injuries
Dr. Mulvaney also has documented experience in medical teaching and research, supporting his broader work in regenerative and image-guided treatments.
5. Dr. Dean Reeves, MD – Kansas
Dr. Dean Reeves, MD, is a physician with a strong background in Physical Medicine and Rehabilitation, focusing on musculoskeletal pain and prolotherapy.
His clinical and research work has contributed to the field of regenerative medicine in the United States.
His expertise includes:
- Dextrose and platelet prolotherapy
- Chronic musculoskeletal pain
- Sprains, strains, and joint problems
- Prolotherapy research and clinical practice
Dr. Reeves co-authored a major review of dextrose prolotherapy covering basic science, clinical research, and treatment considerations.
His long-standing involvement in prolotherapy combines clinical experience with academic research.
6. Dr. David Wang, DO – Washington, DC
Dr. David Wang, DO, is a Physical Medicine and Rehabilitation physician known for his work in musculoskeletal ultrasound and regenerative medicine.
His clinical and teaching experience has helped advance image-guided regenerative care in America.
His professional focus includes:
- Prolotherapy and regenerative orthobiologics
- PRP treatments
- Diagnostic and interventional musculoskeletal ultrasound
- Physical Medicine and Rehabilitation
Dr. Wang completed his residency at Harvard Medical School/Spaulding Rehabilitation Hospital and has taught prolotherapy and regenerative medicine nationally and internationally since 2008.
His combination of clinical practice and education makes him a notable specialist in this field.
7. Dr. Mayo Friedlis, MD – Virginia/Maryland
Dr. Mayo Friedlis, MD, specializes in interventional pain medicine and Physical Medicine and Rehabilitation, with experience in image-guided injections and regenerative treatments.
His clinical work covers a range of musculoskeletal and spine-related conditions in the United States.
His areas of expertise include:
- Prolotherapy and regenerative treatments
- Interventional pain medicine
- Image-guided injections
- Musculoskeletal and spine conditions
Dr. Friedlis is board-certified in Physical Medicine and Rehabilitation, and his current physician profile specifically lists prolotherapy among his treatment options.
He has also been featured by the American Academy of Orthopedic Medicine in educational material covering prolotherapy, PRP, and stem-cell treatments.
8. Dr. Steven Karageanes, DO – Michigan
Dr. Steven Karageanes, DO, is a sports medicine physician in Michigan with particular experience in orthopedic, sports, and performing-arts injuries.
His practice provides non-surgical regenerative treatment options for patients in America.
His clinical focus includes:
- Prolotherapy and PRP
- Sports medicine
- Diagnostic musculoskeletal ultrasound
- Performing-arts and sports-related injuries
Dr. Karageanes has worked with dancers, performing artists, athletic programs, and professional productions.
His combination of sports medicine experience and regenerative treatment expertise makes him a notable physician in this field.
9. Dr. Mark Cantieri, DO – Indiana
Dr. Mark Cantieri, DO, has extensive experience in osteopathic medicine, musculoskeletal pain care, and prolotherapy.
He has practiced in the South Bend and Mishawaka area and has focused much of his career on musculoskeletal conditions.
His professional experience includes:
- Prolotherapy since 1997
- Musculoskeletal pain treatment
- Prolotherapy education and physician training
- Regenerative medicine
Dr. Cantieri has taught prolotherapy to physicians in the US and internationally and co-authored Principles of Prolotherapy, a medical textbook on the technique.
His long-term clinical and educational involvement is a key part of his professional profile.
10. Dr. Suzanne Alt, DO – Missouri
Dr. Suzanne Alt, DO, is an osteopathic physician whose professional areas include prolotherapy, Physical Medicine and Rehabilitation, and musculoskeletal care.
Her background combines osteopathic medicine with regenerative treatment approaches.
Her areas of focus include:
- Prolotherapy
- Physical Medicine and Rehabilitation
- Pain management
- Musculoskeletal care
The American Osteopathic Association of Prolotherapy Regenerative Medicine lists Dr. Alt as prolotherapy board-certified.
A physician directory also identifies prolotherapy among her specialties, supporting her experience in regenerative and musculoskeletal care in the United States.
Comparison of the Top Prolotherapy Specialists
Choosing a prolotherapy specialist often depends on their location, clinical focus, and experience.
The table below gives you a simple overview of these specialists and their main areas of expertise.
| Specialist | Location | Prolotherapy Focus | Specialty |
| Dr. Blanki Cherubini, MD | Rhode Island | Regenerative care | Pain & rehab |
| Dr. Donna Alderman, DO | California | Dextrose & PRP | Regenerative medicine |
| Dr. Ross Hauser, MD | Florida | H3 Prolotherapy | Spine & joint care |
| Dr. Sean Mulvaney, MD | Maryland | Prolotherapy & PRP | Sports medicine |
| Dr. Dean Reeves, MD | Kansas | Dextrose therapy | Pain & rehab |
| Dr. David Wang, DO | Washington, DC | Prolotherapy & PRP | Regenerative medicine |
| Dr. Mayo Friedlis, MD | VA/Maryland | Prolotherapy | Pain medicine |
| Dr. Steven Karageanes, DO | Michigan | Prolotherapy & PRP | Sports medicine |
| Dr. Mark Cantieri, DO | Indiana | Prolotherapy | Musculoskeletal care |
| Dr. Suzanne Alt, DO | Missouri | Prolotherapy | Pain & rehabilitation |
What Conditions Can Prolotherapy Specialists Treat?
Prolotherapy is mainly used in some practices for musculoskeletal conditions involving joints, ligaments, tendons, and other connective tissues.
Depending on the physician’s training, it may be considered for:
- Chronic joint pain
- Ligament injuries
- Tendon injuries and tendinopathy
- Osteoarthritis-related pain
- Low-back pain
- Neck pain
- Sports injuries
- Joint instability
- Certain overuse injuries
However, the evidence varies by condition.
Cleveland Clinic notes that prolotherapy is not a standard treatment for any particular disease or condition, while published research continues to investigate its potential role in musculoskeletal pain.
How Much Does Prolotherapy Cost in the US?
Prolotherapy costs vary across the United States based on the provider, treatment area, number of injections, and sessions required.
As a general guide, one prolotherapy session may cost around $200–$500.
Costs may also include:
- Initial consultation: Often charged separately
- Ultrasound guidance: May add to the treatment fee
- Multiple sessions: Increase the overall cost
- Insurance: Coverage can be limited or unavailable
Before treatment, ask the clinic for a complete cost estimate and confirm whether any part of the treatment is covered by your insurance.
How to Choose the Right Prolotherapy Specialist
Finding the right physician is about more than choosing a name from a list. Consider whether the doctor regularly treats your specific condition and has appropriate medical training.
Look for a specialist who:
- Has documented experience with prolotherapy.
- Understands your specific injury or pain condition.
- Can explain the expected benefits and limitations.
- Discusses conventional and alternative treatment options.
- Uses imaging guidance when appropriate.
- Clearly explains the number and cost of planned treatments.
- Reviews potential risks and alternatives.
- Does not promise guaranteed results.
It is also worth asking whether prolotherapy is appropriate for your particular diagnosis.
Since the evidence is still developing, an informed discussion with a qualified physician can help you understand where it fits among other treatment options.
Final Thoughts
The United States has physicians with diverse experience in prolotherapy and regenerative medicine, including physical medicine, rehabilitation, sports medicine, and pain management.
The specialists featured in this guide have documented clinical, educational, or research experience related to prolotherapy and musculoskeletal care.
Before choosing a specialist, consider their credentials, experience with your condition, treatment approach, costs, and the available evidence. A consultation can help determine whether prolotherapy is appropriate for you.
